Stabbing chest pain worse on taking a deep breath.
Rapid heart rate
An unexplained cough sometimes with bloody mucus
Apprehension, anxiety
Sweating
Feeling faint
Fatigue
Some people may be asymptomatic
Signs and symptoms in thrombophilic conditions
Pregnancy loss
Recurrent pregnancy loss and miscarriage could be due to clotting disorder (thrombophilia) especially in females with Factor V Leiden mutation, prothrombin gene mutation, antiphospholipid syndrome or lupus anticoagulants and in women with protein C & S and antithrombin deficiencies.
Pregnancy loss and recurrent miscarriage may be due to excessive clotting in the small placental vessels.
Inherited deficiencies
Mesenteric vein clots are rare but characteristic of an inherent clotting disorder.
A family history of blood clots.
Blood clots in persons under 40 years
Neo-natal Purpura fulminans is rare and associated with homozygous protein C & S deficiencies.
These patients are mostly asymptomatic and diagnosed because of a family history suggestive of a clotting disorder.
Superficial thrombophlebitis
They block the blood flow in the veins below the skin causing pain and irritation.
Redness and inflammation along the vein may be seen
There are warmth, tenderness, and itching along the vein
Pain along the vein – throbbing or burning – may interfere with sleep.
May develop a fever along with episodes of thrombophlebitis.
Hyperhomocysteinemia
Clinical signs are like those of other clotting disorders
Patients with significant Hyperhomocysteinemia develop DVT with or without PE in 64%; superficial thrombophlebitis in 24%; Thrombosis of the mesenteric or cerebral veins in 12%.
Clotting signs are associated with other triggering factors like oral contraceptives, trauma/surgery, pregnancy, and immobilization.